The CNTF neural factor appears to act only on the nervous system and is thought to promote neurotransmitter synthesis and neurite outgrowth in some neuronal populations.
It is potent survival factor for neurons and oligodendrocytes.
Alternative names
Recombinant Rat Ciliary Neurotrophic Factor, HCNTF, CNTF, Ciliary Neurotrophic Factor.
Fully biologically active by its ability to phosphorylate STAT3 in several cells lines.
Solubility & Handling
Solubility overview
To make a stock solution, reconstitute in sterile water or 0.4% NaHCO3 adjusted to pH 8-9, at a concentration > 100μg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein.
Handling
Solutions should be made in sterile deionized water (not less than 100 µg/ml). This solution can then be further diluted with other aqueous solutions.
Following reconstitution, solutions may be stored at 4°C and are useable for around 2-7 days and for future use store at -18°C.
Freeze-thaw cycles should be prevented.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Understanding purity and quality - a guide for life scientists
