DREADD
Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).
Evans blue (HB0280)
Description:Potent AMPA / kainate receptor antagonist. Vesicular L-glutamate uptake inhibitor.
Fura-2 AM (Cell permeant) (HB0780)
Description:High affinity, cell permeable calcium indicator which is ratiometric and UV light excitable
Hoechst 33342 (HB0787)
Description:Blue fluorescent DNA stain. Cell permeable. Nuclear stain.
Purity:>98%
- Description:
Blue fluorescent DNA stain. Nuclear stain. 10mg/ml staining solution in water. Solid also available in 50mg and 100mg.
JC-1 (HB0791)
Description:Mitochondrial membrane potential indicator/dye. Widely used in apoptosis studies.
Purity:>95%