Kinase
Protein kinases (phosphotransferases) are enzymes that catalyze phosphorylation. They phosphorylate specific amino acids using ATP as the source of phosphate. In this way, the biological activity of proteins is regulated; phosphorylation induces a conformational change from an inactive to an active form of the protein. Researchers can save up to 50% on kinase inhibitors and activators from Hello Bio - they are up to half the price of other suppliers.Â
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5-Azacytidine (HB1374)
Description:DNA methyltransferase inhibitor. Improves stem cell reprogramming efficiency and induces differentiation of MSCs into cardiomyocytes.
Purity:>98%
BIX 01294 (HB1413)
Description:Potent, selective GLP / G9a HMTase inhibitor. Potentiates iPSC induction.
Purity:>98%
CHIR 99021 (HB1261)
Description:Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons.
Purity:>98%
CHIR 99021 trihydrochloride (HB1262)
Description:Potent, selective GSK3 inhibitor and Wnt signaling activator. Commonly used in organoid production and involved in reprogramming MEFs to IPSCs and fibroblasts to mature neurons. Water soluble.
Purity:>98%
DBZ (Dibenzazepine) (HB3419)
Description:γ-secretase and Notch pathway inhibitor. Stimulates iPSC formation.
Purity:>99%
3-Deazaneplanocin A hydrochloride (HB1416)
Description:Histone methyltransferase inhibitor. Enhances Oct4 expression in chemically-induced pluripotent stem cells.
Purity:>98%
Kenpaullone (HB1266)
Description:Potent CDK inhibitor. Also GSK-3 inhibitor. Generates iPSCs.
Purity:>98%
PD 0325901 (HB2240)
Description:Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.
Purity:>98%
Pifithrin-μ (HB3025)
Description:p53 inhibitor. Supresses eSC self renewal and may increase stem cell reprogramming efficiency.
Purity:>99%
RepSox (HB3301)
Description:Potent, selective TGF-βRI inhibitor. Enhances cellular reprogramming efficiency.
Purity:>99%