Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Antibody to GFAP - cytoskeletal protein used as an astrocyte marker. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Chicken
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μL
    Price:
    $164
    Qty:
    Pack:
    100μL
    Price:
    $366
    Qty:
  2. Description:

    Antibody to GFP - green coloured fluorescent protein widely used as a tag in molecular biology. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Chicken
    Clonality: Polyclonal
    Reactivity Tested: Species Independent
    Pack:
    25μg
    Price:
    $140
    Qty:
    Pack:
    100μg
    Price:
    $311
    Qty:
  3. Description:

    Antibody to tyrosine hydroxylase (TH) - the rate limiting enzyme in catecholamine synthesis and used as a marker for catecholaminergic (dopaminergic and noradrenergic) neurones in the CNS. Part of the ValidAb™ range of highly validated, data-rich antibodies.

    Host: Chicken
    Clonality: Polyclonal
    Reactivity Tested: Mouse, Rat
    Pack:
    25μg
    Price:
    $91
    Qty:
    Pack:
    100μg
    Price:
    $272
    Qty: