Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. Description:

    Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $66
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    5mg
    Price:
    $312
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    10mg
    Price:
    $123
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    Pack:
    50mg
    Price:
    $488
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  3. Pack:
    10mg
    Price:
    $147
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    Pack:
    50mg
    Price:
    $602
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    Description:

    Selective negative allosteric modulator of GluN2B (NR2B) containing NMDARs

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $61
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    Pack:
    10mg
    Price:
    $130
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    Pack:
    50mg
    Price:
    $540
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  5. Pack:
    50mg
    Price:
    $495
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