Histone deacetylase (HDAC)
Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.
- Description:
Goat Anti-Mouse IgG H&L (Biotin) preadsorbed secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: GoatClonality: Polyclonal
- Description:
Goat Anti-Rabbit IgG H&L (Biotin) preadrorbed secondary antibody. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: GoatClonality: Polyclonal -
Anti-Parvalbumin antibody ValidAb™ (HB6457)
Description:Antibody to Parvalbumin - calcium binding protein used as a marker for an inhibitory interneuron subtype. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat -
Streptavidin-HRP (HB5225)
Description:Biotin binding protein conjugated with HRP for colormetric detection in IHC and chemiluminescent detection in WB
- Description:
Antibody to tyrosine hydroxylase (TH) - the rate limiting enzyme in catecholamine synthesis and used as a marker for catecholaminergic (dopaminergic and noradrenergic) neurones in the CNS. Part of the ValidAb™ range of highly validated, data-rich antibodies.
Host: MouseClonality: MonoclonalReactivity Tested: Mouse, Rat
