Target

Potent, selective, non-competitive mGlu₁ antagonist

Potent, selective BET bromodomain inhibitor. Cell permeable.

Potent, reversible p38α MAPK inhibitor

Non-selective protein kinase inhibitor

Potent PKC and casein kinase II inhibitor

PKC inhibitor

Prototypic, selective kainate receptor agonist. Potent excitant and neurotoxin.

Selective, reverse mode Na⁺ / Ca²⁺ exchange inhibitor

Atypical voltage-gated sodium channel blocker

Novel, selective Piezo1 channel activator. Improved efficacy and potency compared to Yoda1.