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Biological Data
| Biological description | Potent protein kinase C (PKC) and casein kinase II inhibitor (IC50 = 38.3 nM at PKC). Inhibits neurotrophic factor and nerve growth factor. |
Solubility & Handling
| Solubility overview | Soluble in DMSO (1mg/ml) or DMF (1mg/ml) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | Staurosporine Aglycone |
| Chemical structure | ![K-252b [99570-78-2] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "K-252b [99570-78-2]") |
| Molecular Formula | C26H19N3O5 |
| PubChem identifier | 9846716 |
| SMILES | CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)O)O |
References for K-252b
References are publications that support the biological activity of the product
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K-252b, c and d, potent inhibitors of protein kinase C from microbial origin.
Nakanishi S et al (1986) J Antibiot (Tokyo) 39(8) : 1066-71. -
K-252b, c and d, potent inhibitors of protein kinase C from microbial origin.
Nakanishi S et al (1986) J Antibiot (Tokyo) 39(8) : 1066-71.
Potent PKC and casein kinase II inhibitor
![K-252b [99570-78-2] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb0352.png "K-252b [99570-78-2]")
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