Target

Potent PORCN inhibitor. Supresses R1 ESCs self renewal.

Cell permeable, non-fluorescent F-actin probe. Induces actin polymerization and stabilization.

Piezo1 channel activator

Novel, inactive photocaged derivative of raseglurant which can be uncaged with violet light. Shows light-dependent analgesic activity in vivo.

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Freebase.

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Freebase.

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.

Jumonji histone demethylase inhibitor

Downstream Hedgehog signaling pathway inhibitor. Alcohol dehydrogenase 7 inhibitor.