Target

Potent, selective AMPK inhibitor. Promotes neural hPSCs differentiation and promotes cardiomyocyte differentiation in mESCs.

Potent, selective A₁ receptor inverse agonist

Selective ERβ estrogen receptor agonist

Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant. Water soluble.

Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant.

Potent 5-HT and NA reuptake inhibitor. Also inhibits dopamine reuptake.

Cell-permeable, non-competitive dynamin inhibitor

Potent, selective K_v11.1 channel blocker

Group I / II mGlu antagonist

Potent, selective CaM antagonist