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L-DOPA methyl ester hydrochloride

(HB5354)
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Product overview

Name L-DOPA methyl ester hydrochloride
Alternative names DME, LDME, Levodopa methyl ester, ST 41769, 3,4-Dihydroxyphenylalanine methyl ester
Purity >98%
Description

Water soluble L-DOPA derivative

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3) Frequently bought together
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L-DOPA methyl ester hydrochloride product vial image | Hello Bio
L-DOPA methyl ester hydrochloride product vial image | Hello Bio

L-DOPA methyl ester hydrochloride product vial image | Hello Bio

L-DOPA methyl ester hydrochloride product vial image | Hello Bio

Biological Data

Biological description

Highly water-soluble derivative of L-DOPA, with better oral bioavailability, solubility and pharmacokinetic profile than L-DOPA. Exhibits anti-parkinsonian action.

Solubility & Handling

Solubility overview

Soluble in water (100 mM)

Storage instructions -20°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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More Info

Dilution

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More Info

Chemical Data

Purity >98%
Chemical name

Methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride

Molecular Weight 247.68
Chemical structure Chemical Structure
Molecular Formula C10H13NO4.HCl
CAS Number 1421-65-4
PubChem identifier 10131132
SMILES COC(=O)[C@H](CC1=CC(=C(C=C1)O)O)N.Cl
InChi InChI=1S/C10H13NO4.ClH/c1-15-10(14)7(11)4-6-2-3-8(12)9(13)5-6;/h2-3,5,7,12-13H,4,11H2,1H3;1H/t7-;/m0./s1
InChiKey WFGNJLMSYIJWII-FJXQXJEOSA-N
MDL number MFCD00038958
Appearance Off-white solid

References for L-DOPA methyl ester hydrochloride

References are publications that support the biological activity of the product

  • Development of a Hydrophobicity-Controlled Delivery System Containing Levodopa Methyl Ester Hydrochloride Loaded into a Mesoporous Silica

    Kiss et al (2021) Pharmaceutics 13(7) : 1039
    Read more (PubMedID: 34371730)

  • Striatal inhibition of PKA prevents levodopa-induced behavioural and molecular changes in the hemiparkinsonian rat

    Lebel et al (2010) Neurobiol Dis. :
    Read more (PubMedID: 20060905)

  • The effects on central dopamine function of chronic L-dopa (methyl ester hydrochloride) treatment of mice

    Tabar et al (1989) Pharmacol Biochem Behav. 139-46. : 33(1)
    Read more (PubMedID: 2789405)

3 Item(s)

Related Products
Grouped product items
Order: HB5354
Pack PriceQty
500mg
$103
1g
$137
5g
$397

Water soluble L-DOPA derivative

Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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