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L-DOPA methyl ester hydrochloride product vial image | Hello Bio
L-DOPA methyl ester hydrochloride product vial image | Hello Bio
Biological Data
| Biological description | Highly water-soluble derivative of L-DOPA, with better oral bioavailability, solubility and pharmacokinetic profile than L-DOPA. Exhibits anti-parkinsonian action. |
Solubility & Handling
| Storage instructions | -20°C |
| Solubility overview | Soluble in water (100 mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use |
Chemical Data
| Chemical name | Methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride |
| Chemical structure |  |
| Molecular Formula | C10H13NO4.HCl |
| PubChem identifier | 10131132 |
| SMILES | COC(=O)[C@H](CC1=CC(=C(C=C1)O)O)N.Cl |
| InChi | InChI=1S/C10H13NO4.ClH/c1-15-10(14)7(11)4-6-2-3-8(12)9(13)5-6;/h2-3,5,7,12-13H,4,11H2,1H3;1H/t7-;/m0./s1 |
| InChiKey | WFGNJLMSYIJWII-FJXQXJEOSA-N |
| Appearance | Off-white solid |
References for L-DOPA methyl ester hydrochloride
References are publications that support the biological activity of the product
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Development of a Hydrophobicity-Controlled Delivery System Containing Levodopa Methyl Ester Hydrochloride Loaded into a Mesoporous Silica
Kiss et al (2021) Pharmaceutics 13(7) : 1039 -
Striatal inhibition of PKA prevents levodopa-induced behavioural and molecular changes in the hemiparkinsonian rat
Lebel et al (2010) Neurobiol Dis. : -
The effects on central dopamine function of chronic L-dopa (methyl ester hydrochloride) treatment of mice
Tabar et al (1989) Pharmacol Biochem Behav. 139-46. : 33(1)
Water soluble L-DOPA derivative
Understanding purity and quality - a guide for life scientists
