Target

Non-selective endogenous glycine receptor agonist 

Potent, reversible, selective K_Ca channel inhibitor

Potent, selective Bruton's tyrosine kinase (BTK) inhibitor.

Potent, selective Na_v1.3 / Na_v1.1 channel inhibitor

Potent, selective cAMP PDE inhibitor

Potent TRPM8 channel agonist

Potent muscarinic acetylcholine receptor superagonist. Also binds the hM3R-miniG_q DREADD receptor.

Piezo1 channel activator

Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.

Prototypic, selective kainate receptor agonist. Potent excitant and neurotoxin.