Target

Non-competitive, GluN2B subunit selective NMDA receptor antagonist

Selective mineralcorticoid receptor antagonist

D₂ receptor antagonist

Potent, selective, non-competitive mGlu₅ antagonist

GABA_A receptor antagonist

Selective PAR₂ peptide antagonist

Broad spectrum glutamate antagonist

5-HT_2A receptor antagonist

Selective, non-competitive AMPA receptor antagonist

Non-competitive AMPA receptor antagonist. Also blocks kainate GluK3 homomeric receptors.