Hedgehog signaling

Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).

Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).

Synthetic PKC activator

Neurogenic agent. Induces SVZ progenitor neuronal differentiation and cardiomyogenic differentiation.

Potently induces chondrogenesis in MSCs

LKB1/AMPK activator. Also promotes neurogenesis.

mTOR activator and autophagy inhibitor. Cell-permeable.

Selective neuronal differentiation inducer in hippocampal neural progenitors

Potent, water-soluble adenylyl cyclase activator

Catalyzes ADP-ribosylation of the G proteins Gα_i, Gα_o and Gα_t