Organoids

Organoids are 3D tissue/organ models made up of pluripotent stem cells and other supporting co-cultured cells eg. epithelial cells. Many types of organoids have been developed to date, including brain, pancreas, heart, lung, intestine, liver, optic cup and cancer organoids. They make stable model systems and can be derived from human stem cells or from patient derived iPSCs. Small molecules are increasingly being used to grow and maintain organoids because of their ease of use and controllable quality, enabling consistent, repeatable results. Researchers can save up to 50% on high purity small molecules used to generate organoids – the range from Hello Bio is around half the price of other suppliers.

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Items 11-14 of 14

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  1. SB 202190 (HB1301)

    Description:

    Potent ATP competitive p38 MAPK inhibitor. 3D growth matrix component, promotes long-term organoid growth and can be used in production of gastric organoids. Promotes stability of human pluripotent stem cells.

    Purity:

    >99%

    Pack:
    5mg
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    Pack:
    10mg
    Price:
    $131
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    Pack:
    25mg
    Price:
    $325
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    Pack:
    50mg
    Price:
    $547
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  2. SB 431542 (HB3555)

    4  Reviews
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    Description:

    Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $109
    Qty:
    Pack:
    5mg
    Price:
    $153
    Free trial
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    Pack:
    2x5mg
    Price:
    $240
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    Pack:
    10mg
    Price:
    $233
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    Pack:
    25mg
    Price:
    $508
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    Pack:
    50mg
    Price:
    $959
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    Pack:
    10mM (1mL in DMSO)
    Price:
    $154
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  3. Trans-ISRIB (HB4567)

    Description:

    Integrated stress response (ISR) inhibitor. Promotes pluripotent stem cell survival as part of the CEPT cocktail.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $120
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    Pack:
    50mg
    Price:
    $415
    Qty:
  4. 7  Reviews
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    Description:

    Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts. Manufactured to a high degree of optical purity.

    Purity:

    >99%

    Pack:
    1mg
    Price:
    $44
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    Pack:
    2mg
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    Pack:
    5mg
    Price:
    $119
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    Pack:
    10mg
    Price:
    $168
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    Pack:
    5x10mg
    Price:
    $754
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    Pack:
    25mg
    Price:
    $325
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    Pack:
    50mg
    Price:
    $564
    Qty:
    Pack:
    10mM solution (in 1mL DMSO)
    Price:
    $172
    Qty:
    Pack:
    50mM (add 1ml water)
    Price:
    $408
    Qty:
    Pack:
    100mM (add 1ml water)
    Price:
    $680
    Qty:
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