Cytoskeleton and Extracellular Matrix
The cytoskeleton acts as a cellular scafforld within a cell and plays an important role in many processes such as cell motility and cell division. Many cytoskeletal proteins interact with proteins of the extracellular matrix (ECM). The ECM is a network of extracellular molecules which provide structural and biochemical support to surrounding. The ECM is vital to cellular processes including proliferation, adhesion, migration, polarity, differentiation, and apoptosis.
Researchers can save up to 50% on Cytoskeleton and Extracellular Matrix products from Hello Bio - they are up to half the price of other suppliers.
View products: Actin | Matrix Metalloproteases (MMP) | PI3K/Akt/mTOR | Microtubule | ROCK (Rho-kinase)
Niclosamide (HB1435)
Description:STAT3 signaling pathway inhibitor. Antineoplastic against AML stem cells.
Purity:>98%
Nocodazole (HB3999)
Description:Mitosis inhibitor, widely used as a cell cycle synchronizing agent. Enhances HDR efficiency and increases Cas9-mediated gene editing frequencies.
Purity:>98%
- Description:
LPA1 and LPA2 agonist. Inhibits differentiation of neural stem cells (NSCs) into neurons.
Purity:>95%
PD 0325901 (HB2240)
Description:Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.
Purity:>98%
PD 173074 (HB3584)
Description:FGFR1/ FGFR3 inhibitor. Inhibits oligodendrocyte progenitor proliferation and differentiation.
Purity:>98%
PD 98059 (HB2244)
Description:Selective MEK1/MAP2K inhibitor. Enhances ESC self-renewal.
Purity:>98%
Pifithrin-μ (HB3025)
Description:p53 inhibitor. Supresses eSC self renewal and may increase stem cell reprogramming efficiency.
Purity:>99%
Pluripotin (HB2223)
Description:Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal.
Purity:>98%
PluriSln 1 (HB3573)
Description:SCD1 inhibitor. Selectively eliminates undifferentiated hPSCs from culture.
Purity:>99%
PNU 74654 (HB0528)
Description:β-catenin inhibitor. Wnt pathway inhibitor. Promotes neural differentiation of hPSCs.
Purity:>99%