Cytoskeleton and Extracellular Matrix
The cytoskeleton acts as a cellular scafforld within a cell and plays an important role in many processes such as cell motility and cell division. Many cytoskeletal proteins interact with proteins of the extracellular matrix (ECM). The ECM is a network of extracellular molecules which provide structural and biochemical support to surrounding. The ECM is vital to cellular processes including proliferation, adhesion, migration, polarity, differentiation, and apoptosis.
Researchers can save up to 50% on Cytoskeleton and Extracellular Matrix products from Hello Bio - they are up to half the price of other suppliers.
View products: Actin | Matrix Metalloproteases (MMP) | PI3K/Akt/mTOR | Microtubule | ROCK (Rho-kinase)
SP600125 (HB2234)
Description:Selective, ATP-competitive JNK inhibitor. Prevents BMP9-induced osteogenic MSC differentiation. Maintains stem cells in naive pluripotent state.
Purity:>98%
Stauprimide (HB3011)
Description:NME2 nuclear translocation inhibitor. Primes ESCs for differentiation.
Purity:>98%
SU 5402 (HB3133)
Description:Potent FGFR and VEGFR inhibitor. Attenuates integrin β4-induced neural stem cell differentiation.
Purity:>95%
Thiazovivin (HB3240)
Description:Rock inhibitor. Improves hESCs survival and fibroblast reprogramming efficiency and iPSCs induction.
Purity:>97%
Trans-ISRIB (HB4567)
Description:Integrated stress response (ISR) inhibitor. Promotes pluripotent stem cell survival as part of the CEPT cocktail.
Purity:>98%
Tranylcypromine hydrochloride (HB1412)
Description:LSD1 / MAO inhibitor. Enables reprogramming of mouse embryonic fibroblasts into iPS cells.
Purity:>98%
Trichostatin A (HB1402)
Description:Potent HDAC inhibitor. Induces hiPSCs differentiation to cardiogenic cells and induces accelerated dedifferentiation of primordial germ cells.
Purity:>98%
Valproic acid sodium salt (HB0867)
Description:Histone deacetylase inhibitor. Shows multitude of biological actions. Enables pluripotent stem cell induction from somatic cells.