AMPA receptor agonist and group I mGlu agonist. Sensitizes hippocampal neurons to depolarization by excitatory amino acid analogues such as L-AP4, and L-AP6 ("the Quis effect"). Can also act as an excitotoxin and is used to lesion areas of the brain in rat models.
Solubility & Handling
Solubility overview
Soluble in NaOH(aq) (100mM, 1eq. NaOH) or water (10mM)
Storage instructions
Room temperature
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.