Product overview

Name CX 614
Alternative names BDP-37
Purity >99%
Description

AMPA receptor positive allosteric modulator (PAM)

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Biological Data

Biological description

AMPA receptor positive allosteric modulator (PAM) that binds at an allosteric site (subsite A) only. Modulates channel deactivation and desensitization and shows antidepressant-like activity. Rapidly upregulates BDNF levels. Active in vivo.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in DMSO (100mM) or ethanol (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one, 2H,3H,6aH-Pyrrolidino[2",1"-3′,2′]1,3-oxazino[6′,5′-5,4]benzo[e]1,4-dioxan-10-one
Molecular Weight 247.25
Chemical structure CX614 [191744-13-5] Chemical Structure
Molecular Formula

C13H13NO4

CAS Number 191744-13-5
PubChem identifier 6451148
SMILES O=C2N4C(CCC4)OC1=CC3=C(OCCO3)C=C12
Source Synthetic
InChiKey RQEPVMAYUINZRE-UHFFFAOYSA-N
Appearance white solid