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(R,S)-MCPG sodium salt product vial image | Hello Bio
(R,S)-MCPG sodium salt product vial image | Hello Bio
Biological Data
| Biological description | Water soluble non-selective group I and II mGluR antagonist.
Also competitive antagonist of ACPD sensitive receptors.
Shows no effect on locomotor activity.
(R,S)-MCPG and (S)-MCPG sodium salt also available. (S)-MCPG also available. |
Solubility & Handling
| Storage instructions | Room temperature |
| Solubility overview | Soluble in water (100mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | (RS)-α-Methyl-4-carboxyphenylglycine disodium salt |
| Chemical structure | ![(R,S)-MCPG sodium salt [1303994-09-3] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "(R,S)-MCPG sodium salt [1303994-09-3]") |
| Molecular Formula | C10H9NNa2O4 |
| PubChem identifier | 90488871 |
| SMILES | NC(C)(C(=O)O[Na])c1ccc(cc1)C(=O)O |
| InChiKey | YGOTXTUQJLFNHB-UHFFFAOYSA-L |
References for (R,S)-MCPG sodium salt
References are publications that support the biological activity of the product
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The metabotropic glutamate receptor antagonist (RS)-MCPG produces hyperlocomotion in amphetamine pre-exposed rats.
Kim JH et al (1998) Neuropharmacology 37(2) : 189-97. -
MCPG antagonizes metabotropic glutamate receptors but not long-term potentiation in the hippocampus.
Manzoni OJ et al (1994) Eur J Neurosci 6(6) : 1050-4. -
Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine.
Eaton SA et al (1993) Eur J Pharmacol 244(2) : 195-7.
Water soluble, non-selective group I and II mGluR antagonist
![(R,S)-MCPG sodium salt [1303994-09-3] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb0038.png "(R,S)-MCPG sodium salt [1303994-09-3]")
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