Receptors & Transporters

Potent, selective A₁ receptor inverse agonist

Selective ERβ estrogen receptor agonist

Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant. Water soluble.

Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant.

Potent 5-HT and NA reuptake inhibitor. Also inhibits dopamine reuptake.

Group I / II mGlu antagonist

Synthetic retinoid. Induces neural differentiation of hESCs.

Potent and selective FXR agonist

Ecdysone receptor (EcR) agonist

Selective 5-HT_1B/1D receptor agonist.