Histone deacetylase (HDAC)

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Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

Items 1-10 of 15

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  1. AICAR (HB2152)

    Description:

    AMPK activator. Promotes osteogenic differentiation of bone marrow-derived MSCs.

    Purity:

    >99%

    Pack:
    25mg
    Price:
    $81
    Qty:
  2. L-Ascorbic acid (HB1238)

    Description:

    Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $86
    Qty:
    Pack:
    1g
    Price:
    $28
    Qty:
    Pack:
    25g
    Price:
    $42
    Qty:
    Pack:
    100g
    Price:
    $100
    Qty:
  3. Description:

    Member of the neurotrophin growth factor family. Plays an important role in synaptic plasticity and neurogenesis.

    Pack:
    2μg
    Price:
    $65
    Qty:
    Pack:
    10μg
    Price:
    $260
    Qty:
  4. 1-EBIO (HB1045)

    Description:

    Epithelial KCa channel activator. Promotes ESC differentiation into cardiomyocytes.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $59
    Qty:
    Pack:
    50mg
    Price:
    $193
    Qty:
  5. Pack:
    5mg
    Price:
    $116
    Qty:
    Pack:
    25mg
    Price:
    $476
    Qty:
  6. FH 1 (HB3565)

    Description:

    iPSC-derived hepatocyte differentiation and maturation enhancer

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $134
    Qty:
    Pack:
    50mg
    Price:
    $488
    Qty:
  7. Forskolin (HB1348)

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    Description:

    Cell permeable, reversible adenylyl cyclase activator. Neuronal differentiation inducer. Used in production of liver organoids.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $124
    Free trial
    Qty:
    Pack:
    50mg
    Price:
    $523
    Qty:
  8. ISX 9 (HB3401)

    Description:

    Neurogenic agent. Induces SVZ progenitor neuronal differentiation and cardiomyogenic differentiation.

    Purity:

    >99%

    Pack:
    10mg
    Price:
    $185
    Qty:
  9. Pack:
    10mg
    Price:
    $188
    Qty:
    Pack:
    25mg
    Price:
    $383
    Qty:
  10. Pack:
    100mg
    Price:
    $66
    Qty:
    Pack:
    100mM (add 1ml water)
    Price:
    $41
    Qty:
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