Histone deacetylase (HDAC)

Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.

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  1. L-Ascorbic acid (HB1238)

    Description:

    Antioxidant. Enhances iPSC generation and increases reprogramming efficiency. Supports mesenchymal stem cell proliferation.

    Purity:

    >99%

    Pack:
    100mg
    Price:
    $89
    Qty:
    Pack:
    1g
    Price:
    $29
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    Pack:
    25g
    Price:
    $43
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    Pack:
    100g
    Price:
    $103
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  2. Pack:
    1mg
    Price:
    $165
    Qty:
  3. Description:

    Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $48
    Qty:
    Pack:
    50mg
    Price:
    $188
    Qty:
  4. 21  Reviews
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    Description:

    Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).

    Purity:

    >98%

    Pack:
    10mg
    Price:
    Qty:
    Pack:
    50mg
    Price:
    $246
    Qty:
  5. MHY 1485 (HB7154)

    Description:

    mTOR activator and autophagy inhibitor. Cell-permeable.

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $58
    Qty:
    Pack:
    50mg
    Price:
    $182
    Qty:
  6. 8  Reviews
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    Description:

    Caged glutamate that rapidly and efficiently releases glutamate when photolysed

    Purity:

    >98%

    Pack:
    10mg
    Price:
    $181
    Qty:
    Pack:
    50mg
    Price:
    $746
    Qty:
    Pack:
    10mM (add 1ml water)
    Price:
    $99
    Qty:
    Pack:
    50mM (add 1ml water)
    Price:
    $418
    Qty: