Target

Akt / PDPK1 inhibitor

Potent dual PI3-K/mTOR inhibitor

Syk tyrosine kinase / JAK-1 inhibitor

p53 inhibitor. Supresses eSC self renewal and may increase stem cell reprogramming efficiency.

Potent PKA inhibitor

Potent, selective PKA inhibitor

Broad spectrum protein kinase inhibitor

Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal.

SCD1 inhibitor. Selectively eliminates undifferentiated hPSCs from culture.

Potent CSF-1R inhibitor. Widely used microglia-depletion agent.