ROCK (Rho-kinase)

Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.

Leukemia stem cell activity inhibitor

Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.

Cyclooxygenase inhibitor. Regulates prostate stem cell antigen.

Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.

Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.

Downstream Hedgehog signaling pathway inhibitor. Alcohol dehydrogenase 7 inhibitor.

Potent CDK inhibitor. Also GSK-3 inhibitor. Generates iPSCs.

Wnt signaling inhibitor. Promotes differentiation of hESCs and iPSCs into cardiomyocytes.

STAT3 signaling pathway inhibitor. Antineoplastic against AML stem cells.