Cytokine Storm / Immune response signaling

Cytokine storm describes an excessive immune response to external stimuli with the release of a large amount of pro-inflammatory cytokines. Cytokine storms occur in a range of infections and non-infectious diseases including COVID-19. The cytokine storm involves a variety of immune-related molecules such as interferon, interleukins, chemokines, CSFs and TNF-α. Increase in proinflammatory cytokines results in an influx of immune cells such as macrophages, T-Cells and neutrophils. The immune response to SARS-CoV2 infection also involves various signaling pathways. Researchers can save up to 50% on small molecules that affect cytokine storm and the immune response, as they are up to half the price of other suppliers.

View products: Angiotensin related | Cytokines, chemokines & NF-κB/I-κB | Inflammasomes | JAK/STAT | MAPK Signaling | PI3K/Akt/mTOR | Protease-Activated Receptors | TLR signaling

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Items 11-16 of 16

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  1. PD 0325901 (HB2240)

    Description:

    Potent MEK1 and MEK2 inhibitor. Enhances iPSCs generation. Used in organoid production.

    Purity:

    >98%

    Pack:
    1mg
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    2mg
    Price:
    $29
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    Pack:
    5×2mg
    Price:
    $120
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    Pack:
    10mg
    Price:
    $114
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    Pack:
    50mg
    Price:
    $321
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  2. Rapamycin (HB2779)

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    Description:

    mTOR inhibitor and potent immunosuppressant. Also used in inducible gene editing methods (e.g. CRISPR/Cas9) and promotes hPSC differentiation.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $146
    Free trial
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    Pack:
    5mg
    Price:
    $247
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  3. Pack:
    1mg
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    Pack:
    10mg
    Price:
    $170
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    Pack:
    50mg
    Price:
    $719
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  4. Torin 2 (HB2254)

    Description:

    Potent, selective mTOR inhibitor

    Purity:

    >98%

    Pack:
    25mg
    Price:
    $462
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  5. Pack:
    1mg
    Price:
    Qty:
    Pack:
    5mg
    Price:
    $171
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    Pack:
    25mg
    Price:
    $708
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  6. Pack:
    5mg
    Price:
    $48
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    Pack:
    10mg
    Price:
    $76
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    Pack:
    25mg
    Price:
    $176
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    Pack:
    50mg
    Price:
    $326
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