Product overview
Name | Propidium Iodide |
Description | Red-fluorescent cell viability dye |
Alternative names | PI |
Biological description | Propidium iodide (PI) is a widely used red-fluorescent intercalating agent that binds and labels nucleic acids.
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Purity | >95% |
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Solubility & Handling
Storage instructions | +4°C |
Solubility overview | Soluble in water (5 mM) |
Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
Chemical name | 2,7-Diamino-9-phenyl-10 (diethylaminopropyl)-phenanthridium iodide methiodide |
Molecular Weight | 668.39 |
Chemical structure | |
Molecular Formula | C27H34I2N4 |
CAS Number | 25535-16-4 |
PubChem identifier | 104981 |
SMILES | CC[N+](C)(CC)CCC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N.[I-].[I-] |
InChiKey | XJMOSONTPMZWPB-UHFFFAOYSA-M |
MDL number | MFCD00011921 |
Appearance | Purple solid |
Excitation | 535nM |
Emission | 617nM |
References for Propidium Iodide
References are publications that support the biological activity of the product
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The DNA intercalators ethidium bromide and propidium iodide also bind to core histones.
Banerjee A et al (2014) FEBS Open Bio 4 : 251-9. -
Analysis of apoptosis by propidium iodide staining and flow cytometry.
Riccardi C et al (2006) Nat Protoc 1(3) : 1458-61. -
DNA staining for fluorescence and laser confocal microscopy.
Suzuki T et al (1997) J Histochem Cytochem 45(1) : 49-53.