Product overview
| Name | Propidium Iodide |
| Description | Red-fluorescent cell viability dye |
| Alternative names | PI |
| Biological description | Propidium iodide (PI) is a widely used red-fluorescent intercalating agent that binds and labels nucleic acids.
|
| Purity | >95% |
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Solubility & Handling
| Storage instructions | +4°C |
| Solubility overview | Soluble in water (5 mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | 2,7-Diamino-9-phenyl-10 (diethylaminopropyl)-phenanthridium iodide methiodide |
| Molecular Weight | 668.39 |
| Chemical structure |  |
| Molecular Formula | C27H34I2N4 |
| CAS Number | 25535-16-4 |
| PubChem identifier | 104981 |
| SMILES | CC[N+](C)(CC)CCC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N)N.[I-].[I-] |
| InChiKey | XJMOSONTPMZWPB-UHFFFAOYSA-M |
| MDL number | MFCD00011921 |
| Appearance | Purple solid |
| Excitation | 535nM |
| Emission | 617nM |
References for Propidium Iodide
References are publications that support the biological activity of the product
-
Analysis of apoptosis by propidium iodide staining and flow cytometry.
Riccardi C et al (2006) Nat Protoc 1(3) : 1458-61. -
The DNA intercalators ethidium bromide and propidium iodide also bind to core histones.
Banerjee A et al (2014) FEBS Open Bio 4 : 251-9. -
DNA staining for fluorescence and laser confocal microscopy.
Suzuki T et al (1997) J Histochem Cytochem 45(1) : 49-53.
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