Ion channels
Ion channels are specialised pore-forming membrane proteins that allow ions to pass through the channel pore. They are classifed by their gating mechanism (eg. voltage-gated, ligand-gated, cyclic-nucleotide-gated & mechanosensitive) or ion selectivity (eg. calcium, potassium, sodium, chloride, proton). Researchers can save up to 50% on selective ion channel activators and blockers from Hello Bio - they are up to half the price of other suppliers.
View products: Voltage-Gated Ion Channels | Ligand-Gated Ion Channels (Ionotropic Receptors) | Ionophores | PiezoView Resources: Ion Channel Modulators
A83-01 (HB3218)
Description:Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human hiPSC self renewal, 3D growth matrix component and promotes long-term organoid growth. Aids fibroblast to NSC/cardiomyocyte reprogramming.
Purity:>98%
SB 431542 (HB3555)
Description:Potent, selective TGF-βRI ALK5, ALK4, ALK7 inhibitor. Induces sheet formation, proliferation, differentiation of ESC-derived endothelial cells and replaces SOX2 in reprogramming protocols.3D growth matrix component and can be used in production of organoids.
Purity:>98%
ROCK inhibitor Y-27632 (HB2297)
Description:Y-27632 is a selective ROCK inhibitor. Frequently used 3D growth matrix component and for production of organoids. Also used when inducing neurons from fibroblasts.
Purity:>99%