Kinase
Protein kinases (phosphotransferases) are enzymes that catalyze phosphorylation. They phosphorylate specific amino acids using ATP as the source of phosphate. In this way, the biological activity of proteins is regulated; phosphorylation induces a conformational change from an inactive to an active form of the protein. Researchers can save up to 50% on kinase inhibitors and activators from Hello Bio - they are up to half the price of other suppliers.Â
View products: Akt / PKB | AMPK | Aurora kinase | BTK | CAM Kinase II | Casein kinase | CDK | c-Src | DYRK | ERK | GRK | GSK-3 | Hexokinase | JAK | MAPK | mTOR | Myosin light chain kinase (MLCK) | Non-selective | PKA | PKC | PKG | PI-3K | Protein-serine/threonine kinase | Protein-tyrosine kinase | RIP | ROCK | RSK| Sphingosine kinase | Syk |Raf | View Resources: Enzyme Inhibitors & Activators
BIO (HB1259)
Description:Potent GSK-3α/β inhibitor. Maintains ESC self-renewal and pluripotency.
Purity:>98%
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Cyclopamine (HB2965)
Description:Smo and hedgehog (Hh) signaling inhibitor. Also depletes stem like cancer cells and induces hESCs into endocrine cells.
Purity:>98%
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Flurbiprofen (HB3049)
Description:Cyclooxygenase inhibitor. Regulates prostate stem cell antigen.
Purity:>99%
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Geldanamycin (HB3311)
Description:Selective Hsp90 inhibitor. Breast cancer stem cell inhibitor.
Purity:>98%
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IWP 2 (HB0344)
Description:Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.
Purity:>98%
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JK 184 (HB3179)
Description:Downstream Hedgehog signaling pathway inhibitor. Alcohol dehydrogenase 7 inhibitor.
Purity:>99%
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Kenpaullone (HB1266)
Description:Potent CDK inhibitor. Also GSK-3 inhibitor. Generates iPSCs.
Purity:>98%
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KY 02111 (HB3465)
Description:Wnt signaling inhibitor. Promotes differentiation of hESCs and iPSCs into cardiomyocytes.
Purity:>99%
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Niclosamide (HB1435)
Description:STAT3 signaling pathway inhibitor. Antineoplastic against AML stem cells.
Purity:>98%
