TLR7

Dyrk1A/B inhibitor. Impairs NSCs self-renewal.

Selective TGF-β signaling inhibitor. Induces cardiomyocyte differentiation in ESCs.

Potent Wnt pathway inhibitor and PORCN inhibitor. Suppresses R1 ESC self-renewal. Used in the production of cardiac organoids.

Potent Wnt/β-catenin signaling inhibitor. Induces cardiomyocyte differentiation of hESCs and iPSCs.

Downstream Hedgehog signaling pathway inhibitor. Alcohol dehydrogenase 7 inhibitor.

Potent, reversible p38α MAPK inhibitor

PKC inhibitor

Potent CDK inhibitor. Also GSK-3 inhibitor. Generates iPSCs.

Potent, selective mTOR inhibitor

Wnt signaling inhibitor. Promotes differentiation of hESCs and iPSCs into cardiomyocytes.