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Veratridine

(HB1006)
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Technical documents: SDS CoA Datasheet
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Product overview

Name Veratridine
Purity >98%
Description Na+ channel activator
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews (1) References (4) Frequently bought together
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Veratridine product vial image | Hello Bio
Veratridine product vial image | Hello Bio

Veratridine product vial image | Hello Bio

Veratridine product vial image | Hello Bio

Biological Data

Biological description Na+ channel activator. Binds to active channels and prevents the inactive state. Increases persistent sodium current and intracellular Ca2+. Increases reverse Na+ / Ca2+ exchange current, pump activity and exocytosis. Induces action potentials and extended membrane depolarization.

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in DMSO (50mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name 4α,9-Epoxy-3β-veratroyloxy-5β-cevan-4β, 12,14,16β,17,20-hexaol
Molecular Weight 673.79
Chemical structure Veratridine [71-62-5] Chemical Structure
Molecular Formula C36H51NO11
CAS Number 71-62-5
PubChem identifier 6280
SMILES O=C(C8=CC=C(OC)C(OC)=C8)O[C@H]1CC[C@@]2(C)[C@@]3([H])[C@@](O)1O[C@@]42[C@@]([C@@](C[C@H](O)[C@@]6(O)[C@]([H])5CN7[C@](CC[C@H](C)C7)([H])[C@@](O)6C)(O)[C@@]5(O)C4)([H])CC3
InChiKey FVECELJHCSPHKY-YFUMOZOISA-N

References for Veratridine

References are publications that support the biological activity of the product

  • [Involvement of veratridine-induced increase of reverse Na(+)/Ca(2+) exchange current in intracellular Ca(2+) overload and extension of action potential duration in rabbit ventricular myocytes].

    Kong LH et al (2012) Sheng Li Xue Bao 64(4) : 433-43.
    Read more (PubMedID: 22907304)

  • Mechanism of the persistent sodium current activator veratridine-evoked Ca elevation: implication for epilepsy.

    Fekete A et al (2009) J Neurochem 111(3) : 745-56.
    Read more (PubMedID: 19719824)

  • Effects of veratridine on sodium currents and fluxes.

    Ulbricht W (1998) Rev Physiol Biochem Pharmacol 133 : 1-54.
    Read more (PubMedID: 9600010)

  • Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ oscillations induced by veratridine.

    Maroto R et al (1994) Eur J Pharmacol 270(4) : 331-9.
    Read more (PubMedID: 7805782)

4 Item(s)

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Order: HB1006
Pack PriceQty
10mg
$89
50mg
$363
Na+ channel activator
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Hazardous: $35

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