Na+ channel activator. Binds to active channels and prevents the inactive state. Increases persistent sodium current and intracellular Ca2+. Increases reverse Na+ / Ca2+ exchange current, pump activity and exocytosis. Induces action potentials and extended membrane depolarization.
Solubility & Handling
Solubility overview
Soluble in DMSO (50mM)
Storage instructions
-20°C
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References are publications that support the biological activity of the product
[Involvement of veratridine-induced increase of reverse Na(+)/Ca(2+) exchange current in intracellular Ca(2+) overload and extension of action potential duration in rabbit ventricular myocytes].
Kong LH et al (2012) Sheng Li Xue Bao 64(4) : 433-43.
![Veratridine [71-62-5] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb1006.png "Veratridine [71-62-5]")
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