Prototypic, selective D1-like dopamine receptor partial agonist (Ki values are 1 and ~ 0.5 nM at D1-like receptors (D1 and D5) and ~ 150, ~ 5000 and ~ 1000 nM at D2-like receptors (D2, D3 and D4) respectively).
SKF 38393 facilitates long term potentiation (LTP) via D1 and D5 activation and has also been shown to presynaptically stimulate glutamate release in the hippocampus.
Additionally activates the HPA axis to increase ACTH and corticosterone levels.
Soluble in water (25 mM, warming) and in DMSO (100 mM)
Storage instructions
-20°C (desiccate)
Storage of solutions
Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions
Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
![SKF 38393 hydrobromide [20012-10-6] Chemical Structure](https://cdn.hellobio.com/media/catalog/product//h/b/hb1840.png "SKF 38393 hydrobromide [20012-10-6]")
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