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Images Quinolinic acid product vial image | Hello Bio
Quinolinic acid product vial image | Hello Bio Biological Data Biological description Endogenous NMDA receptor agonist. Shows no activation at GluN1 and GluN2C subunit containing receptors. Displays neurotoxin and pro-inflammatory properties.
Solubility & Handling Storage instructions Room temperature
Solubility overview Soluble in NaOH(aq) (50mM, 1eq. NaOH)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Chemical Data Chemical name Pyridine-2,3-dicarboxylic acid
Chemical structure
Molecular Formula C7 H5 NO4
SMILES OC(=O)C1=C(N=CC=C1)C(O)=O
InChiKey GJAWHXHKYYXBSV-UHFFFAOYSA-N
References for Quinolinic acid References are publications that support the biological activity of the product
Quinolinic acid: an endogenous neurotoxin with multiple targets. Lugo-Huitrón R et al (2013) Oxid Med Cell Longev 2013 : 104024 Quinolinic acid, the inescapable neurotoxin. Guillemin GJ (2012) FEBS J 279(8) : 1356-65. The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits. de Carvalho LP et al (1996) Neurochem Int 28(4) : 445-52. Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Heyes MP et al (1992) Brain 115 ( Pt 5) : 1249-73.
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Endogenous NMDA receptor agonist