Target

K_2P2.1 (TREK-1) modulator. Used with ML336 as part of the CATKLAMP chemogenetic strategy. Selectively and irreversibly activates TREK-1^CG* but not wild-type K_2P2.1 (TREK-1)

Selective K_2P2.1 (TREK-1) and K_2P10.1 (TREK-2) activator

Covalent K_2P2.1 (TREK-1) modulator. Used with CAT335 as part of the CATKLAMP chemogenetic strategy.

Selective K_2P2.1 (TREK-1) and K_2P10.1 (TREK-2) activator