Cytokines, chemokines & NF-κB/I-κB
Cytokines and chemokines play an important role in the modulation of inflammation and acts as key modulators of inflammation by acting through a variety of complex pathways and interactions.
Proinflammatory cytokines activate the IKK complex and closely interact with NF-κB and JAK/STAT signaling.
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AMD 3100 octahydrochloride (HB2739)
Description:Potent, selective CXCR4 antagonist. Mobilizes hematopoietic stem cells.