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D-Serine

(HB0267)
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Product overview

Name D-Serine
Purity >98%
Description NMDA receptor co-agonist
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (4) Reviews (1) References (3) Frequently bought together
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D-Serine product vial image | Hello Bio
D-Serine product vial image | Hello Bio

D-Serine product vial image | Hello Bio

D-Serine product vial image | Hello Bio

Biological Data

Biological description Endogenous NMDA receptor co-agonist. Binds at the glycine site with higher potency than glycine. Induces Ca2+-dependent inactivation of GluN2A subunit-containing NMDA receptors with potential neuroprotective effects.

Solubility & Handling

Solubility overview Soluble in water (100mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name (R)-2-amino-3-hydroxypropanoic acid
Molecular Weight 105.09
Chemical structure D-Serine [312-84-5] Chemical Structure
Molecular Formula C3H7NO3
CAS Number 312-84-5
PubChem identifier 71077
SMILES C([C@H](C(=O)O)N)O
InChi InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
InChiKey MTCFGRXMJLQNBG-UWTATZPHSA-N
MDL number MFCD00004269

References for D-Serine

References are publications that support the biological activity of the product

  • D-Serine-induced Inactivation of NMDA Receptors in Cultured Rat Hippocampal Neurons Expressing NR2A Subunits is Ca(2+) -Dependent.

    Li X et al (2014) CNS Neurosci Ther 20(11) : 951-60.
    Read more (PubMedID: 25042179)

  • Long-term potentiation depends on release of D-serine from astrocytes.

    Henneberger C et al (2010) Nature 463(7278) : 232-6.
    Read more (PubMedID: 20075918)

  • D-amino acids in the brain: D-serine in neurotransmission and neurodegeneration.

    Wolosker H et al (2008) FEBS J 275(14) : 3514-26.
    Read more (PubMedID: 18564180)

3 Item(s)

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Order: HB0267
Pack PriceQty
1g
$33
NMDA receptor co-agonist
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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