Product overview

Name D-Luciferin sodium salt
Biological description

D-luciferin sodium salt is a water-soluble chemiluminescent luciferase substrate which is commonly used for in vivo imaging of the expression of luciferase. It is also frequently used in vitro.

The compound is nontoxic and stable in cells and live animals.


The luciferin substrate can be oxidized by the luciferase enzyme to generate an excited state molecule that emits light.

Purity >98%
Description Chemiluminescent luciferase substrate
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Images

D-Luciferin sodium salt product vial image | Hello Bio

Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (100 mM), and in DMSO (100 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name (4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid sodium salt
Molecular Weight 302.3
Chemical structure D-Luciferin sodium salt | [103404-75-7] Chemical Structure
Molecular Formula C11H7N2NaO3S2
CAS Number 103404-75-7
PubChem identifier 5702588
SMILES C1[C@@H](N/C(=C\2/N=C3C=CC(=O)C=C3S2)/S1)C(=O)[O-].[Na+]
InChiKey BZNVUYVALNTPBG-WJCSTRGMSA-M
MDL number MFCD00044938

References for D-Luciferin sodium salt

References are publications that support the biological activity of the product
  • Biosynthesis-inspired deracemizative production of d-luciferin by combining luciferase and thioesterase.

    Maeda et al (2017) Biochim Biophys Acta Gen Sub 1861(8) : 2112-2118
  • Beyond D-luciferin: expanding the scope of bioluminescence imaging in vivo.

    Adams et al (2014) Curr Opin Chem Biol 21 : 112-20
  • Dynamic bioluminescence imaging for quantitative tumour burden assessment using IV or IP administration of D: -luciferin: effect on intensity, time kinetics and repeatability of photon emission.

    Keyaerts et al (2008) Eur J Nucl Med Mol Imaging. 35(5) : 999-1007

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