TracerBiotinTM (equivalent to Neurobiotin®)

(HB7672)
Technical documents: Datasheet

Product overview

Name TracerBiotinTM (equivalent to Neurobiotin®)
Purity >95%
Description Neuronal tracer
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Biological Data

Biological description

TracerbiotinTM has the same structure as the widely used neurobiotin®. It is a neuroanatomical tracer which is commonly used to label neurons and acts as a gap junction tracer. Low cytotoxicity and high stability. Suitable for use in vivo, slice preparations, whole mounts and cultured cells and can be delivered by routes such as microinjection, intracellular electrodes, cut and scrape loading. Can be detected using avidin or streptavidin systems, by both chromogenic or fluorescence visualization methods and can be fixed with formalin or glutaraldehyde. Non-toxic, remains in cells longer, is more efficiently iontophoresed and has better solubility than biocytin and other neuronal labels. Neurobiotin® is a trademark of Vector Laboratories

Solubility & Handling

Storage instructions -20°C
Solubility overview soluble in water or DMSO
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Chemical name N-(2-Aminoethyl)biotinamide hydrochloride
Molecular Weight 322.85
CAS Number 111822-45-8
SMILES Cl.[H][C@]12CS[C@@H](CCCCC(=O)NCCN)[C@@]1([H])NC(=O)N2

References for TracerBiotinTM (equivalent to Neurobiotin®)

References are publications that support the biological activity of the product
  • A biotin-containing compound N-(2-aminoethyl)biotinamide for intracellular labeling and neuronal tracing studies: comparison with biocytin.

    Kita H et al (1991) Journal of neuroscience methods 37 : 141-50

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