Product overview

Name Thioflavin S (ThioS)
Alternative names ThioS, ThS
Biological description

Fluorescent amyloid β dye with β-sheet binding properties which is commonly used to observe amyloid plaque accumulation and to detect amyloid pathology.

Description

Fluorescent amyloid β dye, used to detect amyloid pathology.

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Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in DMSO (100 mg/ml)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

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Dilution

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Chemical Data

CAS Number 1326-12-1 (Mixture of compounds)

References for Thioflavin S (ThioS)

References are publications that support the biological activity of the product
  • Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model.

    Shin J et al (2021) Scientific reports 11 : 1617
  • Thioflavin-S staining coupled to flow cytometry. A screening tool to detect in vivo protein aggregation.

    Espargaró A et al (2012) Molecular bioSystems 8 : 2839-44
  • Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance.

    Bussière T et al (2004) The American journal of pathology 165 : 987-95

3 Item(s)