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T3 (triiodothyronine)

(HB7470)
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Product overview

Name T3 (triiodothyronine)
Alternative names Thyroid hormone triiodothyronine (T3),
Purity >98%
Description

Thyroid hormone. Frequently used in various stem cell protocols.

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (2) Reviews References (4) Frequently bought together
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Biological Data

Biological description

Thyroid hormone with many biological actions. It is essential for embryogenesis and brain development, T3 increases neuronal differentiation.

It is frequently used as part of various stem cell related protocols:

  • Promotes neuronal differentiation of embryonic neural stem cells (eNSCs)
  • Beneficial for stem cell maintenance and promotes trophoblast differentiation and improves cell survival and passaging efficiency.
  • Used when generating hiPSC-cardiomyocytes (hiPSC-CM)
  • Aids generation of cortical spheroids from hPSCs and culture of 3D spheroids.

Solubility & Handling

Solubility overview Soluble in DMSO (50 mM)
Storage instructions -20°C
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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More Info

Dilution

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More Info

Chemical Data

Purity >98%
Chemical name O-(4-Hydroxy-3-iodophenyl-3,5-diiodo-L-tyrosine
Molecular Weight 650.97
Chemical structure T3 [6893-02-3] Chemical Structure
Molecular Formula C15H12I3NO4
CAS Number 6893-02-3
PubChem identifier 5920
SMILES C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)I)O
InChi InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1
InChiKey AUYYCJSJGJYCDS-LBPRGKRZSA-N

References for T3 (triiodothyronine)

References are publications that support the biological activity of the product

  • Thyroid hormone enhances stem cell maintenance and promotes lineage-specific differentiation in human embryonic stem cells.

    Deng C et al (2022) Stem cell research & therapy 13 : 120
    Read more (PubMedID: 35313973)

  • The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes.

    Ma H et al (2022) Cell stem cell 29 : 795-809.e11
    Read more (PubMedID: 35452598)

  • Thyroid and Glucocorticoid Hormones Promote Functional T-Tubule Development in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

    Parikh SS et al (2017) Circulation research 121 : 1323-1330
    Read more (PubMedID: 28974554)

  • Thyroid hormone promotes neuronal differentiation of embryonic neural stem cells by inhibiting STAT3 signaling through TRα1.

    Chen C et al (2012) Stem cells and development 21 : 2667-81
    Read more (PubMedID: 22468949)

4 Item(s)

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Grouped product items
Order: HB7470
Pack PriceQty
50mg
$32
100mg
$59
250mg
$145

Thyroid hormone. Frequently used in various stem cell protocols.

Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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