Histone deacetylase (HDAC)
Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.
PBS buffer with Tween 20 (20x) (HB8088)
Description:20x wash buffer for use during immunolabeling techniques such as IHC.
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TBS-T with Tween 20 (20x) (HB6971)
Description:20x Tris Buffered Saline wash buffer to remove non-specific binding and for use during immunolabeling techniques such as IHC.
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Antibody penetration buffer (HB9812)
Description:Helps primary and secondary antibodies penetrate the cells of tissue or 3D cell culture when performing immunohistochemistry (IHC) or immuno-labeling
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Native lysis buffer (1x) pH 7.0 (HB4628)
Description:Ready to use cell lysis and protein solubilization buffer
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Native lysis buffer (10x) pH 7.0 (HB9518)
Description:10x cell lysis and protein solubilization buffer
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TBS (25x) (pH 7.4) (HB7121)
Description:Tris Buffered Saline (TBS) wash buffer to remove non-specific binding.
