Histone deacetylase (HDAC)
Histone acetylation is a key epigenetic process - it is upregulated during memory formation but downregulated in numerous neurodegenerative diseases (eg. Alzheimer's disease and Huntington's disease). There are 18 Histone Deacetylase (HDAC) enzymes that are classified into two groups, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided into classes I, II and IV. HDAC inhibitors are a class of compounds that increase acetylation of lysine residues on histone proteins as well as other, nonhistone, proteins by inhibiting the activity of these HDAC enzymes. Researchers can save up to 50% on HDAC inhibitors from Hello Bio - they are up to half the price of other suppliers.
PBS buffer with Tween 20 (20x) (HB8088)
Description:20x wash buffer for use during immunolabeling techniques such as IHC.
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TBS-T with Tween 20 (20x) (HB6971)
Description:20x Tris Buffered Saline wash buffer to remove non-specific binding and for use during immunolabeling techniques such as IHC.
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Preformulated instant powder packets to make artificial cerebrospinal fluid (aCSF) without Mg2+ or Ca2+
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aCSF Instant Powder (packets) (HB9200)
Description:Preformulated instant powder packets to make artificial cerebrospinal fluid (aCSF)
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Antibody penetration buffer (HB9812)
Description:Increases antibody penetration into thick tissue sections or organoids for IHC and immunostaining
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Cesium methanesulfonate (CsMeSo3) (HB8497)
Description:Used in internal/ intracellular solutions for patch clamp electrophysiology
Purity:>98%
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Native lysis buffer (1x) pH 7.0 (HB4628)
Description:Ready to use cell lysis and protein solubilization buffer
