Target

Potent, selective CaM antagonist

Epithelial K_Ca channel activator. Promotes ESC differentiation into cardiomyocytes.

Broad enzyme inhibitor. Inhibits Gq protein signaling.

Synthetic retinoid. Induces neural differentiation of hESCs.

Potent and selective FXR agonist

Ecdysone receptor (EcR) agonist

Ion chelator

Potent adenosine deaminase and PDE2 inhibitor. Supresses spontaneous hESC differentiation. Also maintains pluripotency of hESCs in the absence of exogenous cytokines.

Macrolide antibiotic

Leukocyte elastase inhibitor