Product overview

Name Elaiophylin
Purity >95%
Description Macrolide antibiotic
Write Your Own Review
You're reviewing:Elaiophylin
Rate this item:

Biological Data

Biological description Macrolide antibiotic. Testosterone 5-reductase and Mg2+- ATPase inhibitor. Shows anthelmintic and immunosuppressive actions. Enhances the antifungal actions of rapamycin.

Solubility & Handling

Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >95%
Chemical name Azalomycin-B; Gopalamicin; Salbomycin
Molecular Weight 1025.27
Chemical structure Elaiophylin  [37318-06-2] Chemical Structure
Molecular Formula C54H88O18
CAS Number 37318-06-2
PubChem identifier 6444206
SMILES CC[C@H]1[C@@H](C[C@](O[C@@H]1C)(O)[C@H]([C@H](O)[C@@H]([C@H]2OC(=O)/C=C/C=C/[C@@H]([C@H](OC(=O)/C=C/C=C/[C@@H]2C)[C@H]([C@@H](O)[C@@H]([C@@]3(O[C@@H]([C@H]([C@@H](C3)O[C@@H]4O[C@H]([C@H]([C@H](C4)O)O)C)CC)C)O)C)C)C)C)C)O[C@@H]5O[C@H]([C@H]([C@H](C5)O)O)C

References for Elaiophylin

References are publications that support the biological activity of the product
  • Enhancement of the antifungal activity of rapamycin by the coproduced elaiophylin and nigericin.

    Fang A et al (2000) J Antibiot (Tokyo) 53(2) : 158-62.
  • SNA-4606-1, a new member of elaiophylins with enzyme inhibition activity against testosterone 5 alpha-reductase.

    Nakakoshi M et al (1999) J Antibiot (Tokyo) 52(2) : 175-7.
  • Characterization of the correlation between ATP-dependent aminophospholipid translocation and Mg2+-ATPase activity in red blood cell membranes.

    Beleznay Z et al (1997) Eur J Biochem 243(1-2) : 58-65.

3 Item(s)