Product overview

Name Elaiophylin
Description Macrolide antibiotic
Biological description Macrolide antibiotic. Testosterone 5-reductase and Mg2+- ATPase inhibitor. Shows anthelmintic and immunosuppressive actions. Enhances the antifungal actions of rapamycin.
Purity >95%
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Solubility & Handling

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Chemical name Azalomycin-B; Gopalamicin; Salbomycin
Molecular Weight 1025.27
Chemical structure Product image
Molecular Formula C54H88O18
CAS Number 37318-06-2
PubChem identifier 6444206
SMILES CC[C@H]1[C@@H](C[C@](O[C@@H]1C)(O)[C@H]([C@H](O)[C@@H]([C@H]2OC(=O)/C=C/C=C/[C@@H]([C@H](OC(=O)/C=C/C=C/[C@@H]2C)[C@H]([C@@H](O)[C@@H]([C@@]3(O[C@@H]([C@H]([C@@H](C3)O[C@@H]4O[C@H]([C@H]([C@H](C4)O)O)C)CC)C)O)C)C)C)C)C)O[C@@H]5O[C@H]([C@H]([C@H](C5)O)O)C

References for Elaiophylin

References are publications that support the biological activity of the product
  • Characterization of the correlation between ATP-dependent aminophospholipid translocation and Mg2+-ATPase activity in red blood cell membranes.

    Beleznay Z et al (1997) Eur J Biochem 243(1-2) : 58-65.
  • SNA-4606-1, a new member of elaiophylins with enzyme inhibition activity against testosterone 5 alpha-reductase.

    Nakakoshi M et al (1999) J Antibiot (Tokyo) 52(2) : 175-7.
  • Enhancement of the antifungal activity of rapamycin by the coproduced elaiophylin and nigericin.

    Fang A et al (2000) J Antibiot (Tokyo) 53(2) : 158-62.