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Orexin B (mouse)

(HB5324)
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Product overview

Name Orexin B (mouse)
Biological description Excitatory neuropeptide at orexin receptors (Ki values are 420 and 36 nM for OX1 and OX2 receptors respectively). Orexin B is involved in a many physiological functions (such as feeding regulation, sleep-wake cycle, energy metabolism etc.).
Alternative names Hypocretin-2
Purity >95%
Description Mouse excitatory neuropeptide at orexin OX1/OX2 receptors
Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews (1) References (3) Frequently bought together
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Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (1 mg/ml)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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Dilution

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Chemical Data

Purity >95%
Chemical name RPGPPGLQGRLQRLLQANGNHAAGILTM (modifications: Met-28 = C-terminal amide)
Molecular Weight 2936.43
Chemical structure Orexin B (mouse) | [202801-92-1] Chemical Structure
Molecular Formula C126H215N45O34S
Sequence (one letter) RPGPPGLQGRLQRLLQANGNHAAGILTM
Modifications Met-28 = C-terminal amide
CAS Number 202801-92-1
PubChem identifier 90479795
SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CC(=O)N)NC(=O)CNC(=O)[C@H](CC(=O)N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCCN3C(=O)CNC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCNC(=N)N)N
InChiKey RLVZFBVFVIDDPQ-GWQFQBPDSA-N
MDL number MFCD01635376

References for Orexin B (mouse)

References are publications that support the biological activity of the product

  • Orexin System: The Key for a Healthy Life.

    Chieffi et al (2017) Front Physiol 31;8 : 357
    Read more (PubMedID: 28620314)

  • The sleep-modulating peptide orexin-B protects midbrain dopamine neurons from degeneration, alone or in cooperation with nicotine.

    Guerreiro et al (2015) Mol Phamacol. 87(3) : 525-32
    Read more (PubMedID: 25552485)

  • Orexin/hypocretin: a neuropeptide at the interface of sleep, energy homeostasis, and reward system.

    Tsujino et al (2009) Pharmacol Rev 61(2) : 162-76
    Read more (PubMedID: 19549926)

3 Item(s)

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Grouped product items
Order: HB5324
Pack PriceQty
500μg
$184
Mouse excitatory neuropeptide at orexin OX1/OX2 receptors
Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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