Product overview
| Name | Naltrexone hydrochloride |
| Description | Competitive opioid receptor antagonist |
| Alternative names | NTX |
| Purity | >99% |
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Biological Data
| Biological description | Competitive opioid receptor antagonist (Ki values are 1.55, 7.84 and 0.71 nM at µ, δ and κ receptors respectively). Diminishes alcohol reward and motivation and decreases alcohol drinking. Active in vivo. |
Solubility & Handling
| Storage instructions | Room temperature |
| Solubility overview | Soluble in water (100 mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | (5α)-17-(Cyclopropylmethyl)-4,5-epox y-3,14-dihydromorphinan-6-one hydrochloride |
| Molecular Weight | 377.87 |
| Chemical structure |  |
| Molecular Formula | C20H23NO4.HCl |
| CAS Number | 16676-29-2 |
| PubChem identifier | 5485201 |
| SMILES | C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O.Cl |
| InChi | InChI=1S/C20H23NO4.ClH/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,15,18,22,24H,1-2,5-10H2;1H/t15-,18+,19+,20-;/m1./s1 |
| InChiKey | RHBRMCOKKKZVRY-ITLPAZOVSA-N |
| MDL number | MFCD00069324 |
| Appearance | White solid |
Publications
These publications cite the use of Naltrexone hydrochloride purchased from Hello Bio:
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Synaptic regulation by OPRM1 variants in reward neurocircuitry.
Popova et al (2019) J Neurosci : 2317-18PubMedID: 31109961
Technical guides
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