Naltrexone hydrochloride

(HB2452)
Technical documents: SDS Datasheet

Product overview

Name Naltrexone hydrochloride
Description Competitive opioid receptor antagonist
Alternative names NTX
Purity >99%
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Biological Data

Biological description Competitive opioid receptor antagonist (Ki values are 1.55, 7.84 and 0.71 nM at µ, δ and κ receptors respectively). Diminishes alcohol reward and motivation and decreases alcohol drinking. Active in vivo.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in water (100 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Chemical name (5α)-17-(Cyclopropylmethyl)-4,5-epox y-3,14-dihydromorphinan-6-one hydrochloride
Molecular Weight 377.87
Chemical structure Naltrexone hydrochloride Chemical Structure
Molecular Formula C20H23NO4.HCl
CAS Number 16676-29-2
PubChem identifier 5485201
SMILES C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O.Cl
InChi InChI=1S/C20H23NO4.ClH/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,15,18,22,24H,1-2,5-10H2;1H/t15-,18+,19+,20-;/m1./s1
InChiKey RHBRMCOKKKZVRY-ITLPAZOVSA-N
MDL number MFCD00069324
Appearance White solid
Publications
These publications cite the use of Naltrexone hydrochloride purchased from Hello Bio:
  • Synaptic regulation by OPRM1 variants in reward neurocircuitry.

    Popova et al (2019) J Neurosci : 2317-18
    PubMedID: 31109961

1 Item