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Biological Data
| Biological description | Flavonoid with many biological actions. Also acts as a GABAA positive allosteric modulator and NLRP3 inflammasome activation inhibitor |
Solubility & Handling
| Storage instructions | +4°C |
| Solubility overview | Soluble in DMSO (75 mM), and in ethanol (20 mM) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one |
| Chemical structure | ![Isoliquiritigenin [961-29-5] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "Isoliquiritigenin [961-29-5]") |
| Molecular Formula | C15H12O4 |
| PubChem identifier | 638278 |
| SMILES | C1=CC(=CC=C1/C=C/C(=O)C2=C(C=C(C=C2)O)O)O |
| InChi | InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+ |
| InChiKey | DXDRHHKMWQZJHT-FPYGCLRLSA-N |
References for Isoliquiritigenin
References are publications that support the biological activity of the product
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Phytochemical and Pharmacological Role of Liquiritigenin and Isoliquiritigenin From Radix Glycyrrhizae in Human Health and Disease Models
Ramalingam et al (2018) Front Aging Neurosci 10 : 348 -
A Review: The Pharmacology of Isoliquiritigenin
Peng et al (2015) Phytother Res. 29(7) : 969-77
Flavonoid with many biological actions
![Isoliquiritigenin [961-29-5] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb4213.png "Isoliquiritigenin [961-29-5]")
Understanding purity and quality - a guide for life scientists
