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Galanin (1-29) (rat, mouse)

(HB3205)
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Product overview

Name Galanin (1-29) (rat, mouse)
Biological description

Non-selective galanin receptor agonist (Ki values are 087, 1.48 and 1.47 at GAL1, GAL2 and GAL3 respectively). Shows orexigenic and neuroprotective effects. Also shows anticonvulsant activity to prevent full kindled seizures in rats.

Purity >95%
Description

Non-selective galanin receptor agonist

Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Solubility & Handling

Storage instructions -20°C
Solubility overview Soluble in water (1 mg/ml)
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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x
More Info

Dilution

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More Info

Chemical Data

Purity >95%
Chemical name H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-His-Gly-Leu-Thr-NH2
Molecular Weight 3164.5
Molecular Formula C141H211N43O41
Sequence (one letter) GWTLNSAGYLLGPHAIDNHRSFSDKHGLT
Modifications Thr-29 is C-terminus
CAS Number 114547-31-8
PubChem identifier 44134729
SMILES CCC(C)C(C(=O)NC(CC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CC1=CNC=N1)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NC(CC2=CC=CC=C2)C(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC3=CNC=N3)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)N)NC(=O)C(C)NC(=O)C(CC4=CNC=N4)NC(=O)C5CCCN5C(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C(CC7=CNC8=CC=CC=C87)NC(=O)CN
InChiKey JHQDYHHNJBOXKP-UHFFFAOYSA-N
Appearance White solid

References for Galanin (1-29) (rat, mouse)

References are publications that support the biological activity of the product

  • Involvement of galanin and galanin receptor 1 in nociceptive modulation in the central nucleus of amygdala in normal and neuropathic rats.

    Li SY et al (2017) Scientific reports 7 : 15317
    Read more (PubMedID: 29127424)

  • Homodimerization and internalization of galanin type 1 receptor in living CHO cells.

    Wirz SA et al (2005) Neuropeptides 39 : 535-46
    Read more (PubMedID: 16242774)

  • Hypothalamic degradation of galanin(1-29) and galanin(1-16): identification and characterization of the peptidolytic products.

    Land T et al (1991) Brain research 558 : 245-50
    Read more (PubMedID: 1723638)

3 Item(s)

Related Products
Grouped product items
Order: HB3205
Pack PriceQty
1mg
$177

Non-selective galanin receptor agonist

Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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