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Corticosterone: HBC complex (water soluble)

(HB18515)
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Product overview

Name Corticosterone: HBC complex (water soluble)
Alternative names CORT
Purity >98%
Description

Water soluble cyclodextrin formulation of corticosterone: endogenous gluococorticoid, MR and GR agonist.

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description

Endogenous gluococorticoid. Acts as a mineralcorticoid (MR) and glucocorticoid receptor (GR) agonist. Involved in a wide range of biological processes and shows a variety of effects.

 

This is a water soluble corticosterone formulation composed of a corticosterone – 2-hydroxypropyl-β-cyclodextrin complex (65.4 mg corticosterone per gram of final product).

Solubility & Handling

Storage instructions

Room temperature

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

=
x
x
More Info

Dilution

x
=
x
More Info

Chemical Data

Purity >98%
Chemical name

(11β)-11,21-Dihydroxypregn-4-ene-3,2 0-dione

Molecular Weight 346.46
Chemical structure Corticosterone [50-22-6] Chemical Structure
Molecular Formula

C21H30O4

CAS Number 50-22-6
PubChem identifier 5753
SMILES C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C)O
InChi InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChiKey OMFXVFTZEKFJBZ-HJTSIMOOSA-N
MDL number MFCD00037715
Appearance White solid
Formulation Contains 66.7mg corticosterone per gram of final product.

References for Corticosterone: HBC complex (water soluble)

References are publications that support the biological activity of the product

  • Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver.

    Flynn BP et al (2021) PLoS genetics 17 : e1009737
    Read more (PubMedID: 34375333)

  • Chronic non-social stress affects depressive behaviors but not anxiety in mice.

    Yoon SH et al (2014) The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 18 : 263-8
    Read more (PubMedID: 24976767)

  • Genomic and non-genomic effects of glucocorticoids on aggressive behavior in male rats.

    Mikics E et al (2004) Psychoneuroendocrinology 29 : 618-35
    Read more (PubMedID: 15041085)

3 Item(s)

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Grouped product items
Order: HB18515
Pack PriceQty
100mg
$110

Water soluble cyclodextrin formulation of corticosterone: endogenous gluococorticoid, MR and GR agonist.

Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

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