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Corticosterone: HBC complex (water soluble)

(HB18515)
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Product overview

Name Corticosterone: HBC complex (water soluble)
Alternative names CORT
Purity >98%
Description

Water soluble cyclodextrin formulation of corticosterone: endogenous gluococorticoid, MR and GR agonist.

Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (1) Reviews References (3)
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Biological Data

Biological description

Endogenous gluococorticoid. Acts as a mineralcorticoid (MR) and glucocorticoid receptor (GR) agonist. Involved in a wide range of biological processes and shows a variety of effects.

 

This is a water soluble corticosterone formulation composed of a corticosterone – 2-hydroxypropyl-β-cyclodextrin complex (65.4 mg corticosterone per gram of final product).

Solubility & Handling

Storage instructions

Room temperature

Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use

Calculators

Molarity

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x
More Info

Dilution

x
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x
More Info

Chemical Data

Purity >98%
Chemical name

(11β)-11,21-Dihydroxypregn-4-ene-3,2 0-dione

Molecular Weight 346.46
Chemical structure Corticosterone [50-22-6] Chemical Structure
Molecular Formula

C21H30O4

CAS Number 50-22-6
PubChem identifier 5753
SMILES C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C)O
InChi InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChiKey OMFXVFTZEKFJBZ-HJTSIMOOSA-N
MDL number MFCD00037715
Appearance White solid
Formulation Contains 66.7mg corticosterone per gram of final product.

References for Corticosterone: HBC complex (water soluble)

References are publications that support the biological activity of the product

  • Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver.

    Flynn BP et al (2021) PLoS genetics 17 : e1009737
    Read more (PubMedID: 34375333)

  • Chronic non-social stress affects depressive behaviors but not anxiety in mice.

    Yoon SH et al (2014) The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 18 : 263-8
    Read more (PubMedID: 24976767)

  • Genomic and non-genomic effects of glucocorticoids on aggressive behavior in male rats.

    Mikics E et al (2004) Psychoneuroendocrinology 29 : 618-35
    Read more (PubMedID: 15041085)

3 Item(s)

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Grouped product items
Order: HB18515
Pack PriceQty
100mg
$110

Water soluble cyclodextrin formulation of corticosterone: endogenous gluococorticoid, MR and GR agonist.

Shipping Info

Standard: $35

Hazardous: $35

Shipped on ice: $35

Shipping will be calculated at checkout

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