Product overview

Name CGP 54626 hydrochloride
Purity >98%
Description Potent, selective GABAB receptor antagonist
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Biological Data

Biological description

Potent and selective GABAB receptor antagonist (IC50 = 4 nM).

Solubility & Handling

Solubility overview Soluble in DMSO (50mM, gentle warming) or ethanol (10mM)
Storage instructions Room temperature
Storage of solutions Prepare and use solutions on the same day if possible. Store solutions at -20°C for up to one month if storage is required. Equilibrate to RT and ensure the solution is precipitate free before use.
Shipping Conditions Stable for ambient temperature shipping. Follow storage instructions on receipt.
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name

[S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl) phosphinic acid

Molecular Weight 444.76
Chemical structure CGP 54626 hydrochloride  [149184-21-4] Chemical Structure
Molecular Formula C18H28Cl2NO3P.HCl
CAS Number 149184-21-4
PubChem identifier 197583
SMILES OP(CC1CCCCC1)(C[C@@H](O)CN[C@@H](C)C2=CC(Cl)=C(Cl)C=C2)=O.Cl
Source Synthetic
InChi InChI=1S/C18H28Cl2NO3P.ClH/c1-13(15-7-8-17(19)18(20)9-15)21-10-16(22)12-25(23,24)11-14-5-3-2-4-6-14;/h7-9,13-14,16,21-22H,2-6,10-12H2,1H3,(H,23,24);1H/t13-,16-;/m0./s1
InChiKey ZQCFHOVIXCJPLE-LINSIKMZSA-N
Appearance White solid

References for CGP 54626 hydrochloride

References are publications that support the biological activity of the product
  • Solubilization and characterization of GABAB receptor binding sites from porcine brain synaptic membranes.

    Facklam M et al (1993) Br J Pharmacol 110(4) : 1291-6.

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