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Arcaine sulfate

(HB0118)
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Technical documents: SDS CoA Datasheet
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Product overview

Name Arcaine sulfate
Purity >99%
Description Competitive NMDA receptor antagonist / NOS inhibitor
Biological Data Solubility & Handling Chemical Data Related Areas Calculators Technical guides (4) Reviews References (4)
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Biological Data

Biological description Competitive NMDA receptor antagonist. Binds at the polyamine site. Also a NOS (Nitric oxide synthase) inhibitor. Reduces NMDA single-channel currents in a voltage-dependent manner.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in water (25mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >99%
Chemical name N,N'-1,4-Butanediylbisguanidine sulfate
Molecular Weight 270.31
Chemical structure Arcaine sulfate [14923-17-2] Chemical Structure
Molecular Formula C6H16N6.H2SO4
CAS Number 14923-17-2
PubChem identifier 119020
SMILES C(CCN=C(N)N)CN=C(N)N.OS(=O)(=O)O
InChiKey RWTGFMPOODRXIM-UHFFFAOYSA-N

References for Arcaine sulfate

References are publications that support the biological activity of the product

  • Spermine and arcaine block and permeate N-methyl-D-aspartate receptor channels.

    Araneda RC et al (1999) Biophys J 76(6) : 2899-911.
    Read more (PubMedID: 10354418)

  • Investigation of the actions and antagonist activity of some polyamine analogues in vivo.

    Doyle KM et al (1998) Br J Pharmacol 124(2) : 386-90.
    Read more (PubMedID: 9641557)

  • Structure-activity relationships of arginine analogues on nitric oxide synthase activity in the rat brain.

    Yokoi I et al (1994) Neuropharmacology 33(11) : 1261-5.
    Read more (PubMedID: 7532812)

  • Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor.

    Reynolds IJ (1990) Eur J Pharmacol 177(3) : 215-6.
    Read more (PubMedID: 2155812)

4 Item(s)

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Grouped product items
Order: HB0118
Pack PriceQty
50mg
$85
Competitive NMDA receptor antagonist / NOS inhibitor
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